Education
Doctor of Philosophy (Toxicology) – University of Georgia, 1998
Master of Science (Physiology) – University of Georgia, 1996
Bachelor of Science – Higher Inst. Zootech. & Vet. Med., Bulgaria, 1990
Honors, Awards, and Achievements
2004 – Society of Toxicology / American Chemistry Council Early Career Award
2004 – Pfizer Award for Research Excellence
2005 – Member, Sigma Xi Scientific Research Society
2005 – Honorary Member, Phi Zeta, The Honor Society of Veterinary Medicine
2005 – Fellow, Institute for Neurocognitive Science and Technology (INST)
2006 – Sigma Xi Ralph Powe Research Award
2007 – Outstanding Faculty Research Award for the College of Veterinary Medicine, Mississippi State University Office of Research and Economic Development
2008 – Member, Editorial Board of Journal of Applied Toxicology
2009 – 2012 – Member, Editorial Board of NeuroToxicology
2011 – Member, Editorial Board of Frontiers in Toxicogenomics
2008 – Ad hoc Member of various NIH Study Sections, i.e., NAL, DBD, MD86
2013 – Associate Editor of NeuroToxicology
2013 – Member, Editorial Board of Toxicology Letters
2016 – 2020 – Regular member of the NURE study section of the VA
2018 – Fellow, Academy of Toxicological Sciences (ATS)
2019 – Lalita and Raghubir Sharma Distinguished Professor in Toxicology, College of Veterinary Medicine, University of Georgia
2020 – Member, Editorial Board of Toxicological Sciences
2020 – Zoetis Award for Research Excellence
2020-2021 – President, Neurotoxicology Specialty Section of the Society of Toxicology
Research Interests
Neuroimmunotoxicology, Neurotoxicology, Immunotoxicology, Pesticides, Metals, Fescue Toxicosis, Environmental perturbations of the integrome
Selected Publications
Krishna, S., M. M. Keralapurath, Z. Lin#, J. J. Wagner, C. B. de La Serre, D. A. Harn, and N. M. Filipov*. (2015). Neurochemical and electrophysiological deficits in the ventral hippocampus and selective behavioral alterations caused by high-fat diet in female C57BL/6 mice. Neuroscience. 297:170-181. Epub: April 4, 2015. PMID: 25849614
Krishna, S., C. A. Dodd, and N. M. Filipov*. (2016). Behavioral and monoamine perturbations in adult male mice with chronic inflammation induced by repeated peripheral lipopolysaccharide administration. Behavioural Brain Research. 302: 279–290. Epub: January 21, 2016. PMID: 26802725
Krishna , S., Z. Lin, C. B. de La Serre, J. J. Wagner, D. A. Harn, L. M. Pepples, D. M. Djani, M. T. Weber, L. Srivastava, and N. M. Filipov*. (2016). Time-dependent behavioral, neurochemical, and metabolic dysregulation in female C57BL/6 mice caused by chronic high-fat diet intake. Physiology and Behavior. 157: 196-208. Epub: February 4, 2016, PMID: 26852949
Mote R. S., N. S. Hill, K. Uppal, V. T. Tran, D. P. Jones, N. M. Filipov*. (2017). Metabolomics of fescue toxicosis in grazing beef steers. Food and Chemical Toxicology. 105:285-299. Epub: April 18, 2017. PMID: 28428084
Pati, S., S. Krishna , J. H. Lee, M. K. Ross, C. B. de La Serre, D. A. Harn, Jr., J. J. Wagner, N. M. Filipov*, and B. S. Cummings*. (2018). Effects of high-fat diet and age on the blood lipidome and circulating endocannabinoids of female C57BL/6 mice. BBA Molecular and Cell Biology of Lipids. 1863(1):26-39. Epub: October 3, 2017. PMID: 28986283
Chen, Y., N. M. Filipov, and T. L. Guo. (2018). Dietary glycation products regulate immune homeostasis: early glycation products promote prostate cancer cell proliferation through modulating macrophages. Molecular Nutrition and Food Research. 62(3), 1700641. Epub: October 30, 2017. PMID: 29082675
Mote, R. S. , N. S. Hill, J. H. Skarlupka, Z. B. Turner, Z. P. Sanders, D. P. Jones, G. Suen, and N. M. Filipov*. (2019). Response of beef cattle fecal microbiota to grazing on toxic tall fescue grazing. (2019). Applied and Environmental Microbiology, 85 (15), pii: e00032-19. Epub: May 24, 2019. PMID: 31126949
Carpenter, J. M., H. E. Gordon, H. D. Ludwig, J. J. Wagner, D. A. Harn, T. Norberg, and N. M. Filipov*. (2019). Neurochemical and neuroinflammatory perturbations in two Gulf War Illness models: Modulation by the immunotherapeutic LNFPIII. Neurotoxicology, 77: 40-50. Epub: December 19, 2019. PMID: 31866310
Brown, K, N. M. Filipov, and J. J. Wagner. 2020. Dorsoventral-specific effects of a sarin surrogate, diisopropylfluorophosphate, on synaptic transmission in the mouse hippocampus. Journal of Pharmacology and Experimental Therapeutics. 373(1): 10-23. Epub: January 6, 2020. PMID: 31907304
Mote, R. S. , N. S. Hill, J. H. Skarlupka, V. T. Tran, D. I. Walker, Z. B. Turner, Z. P. Sanders, D. P. Jones, G. Suen, and N. M. Filipov*. (2020). Toxic tall fescue grazing increases susceptibility of the Angus steer fecal microbiota and plasma/urine metabolome to environmental effects. Scientific Reports, 10(1): 2497. Epub: February 12, 2020. PMID: 32051515
Fang, X., W. Sun, J. Jeon, M. Azain, H. Kinder, J. Ahn, H. C. Chung, R. S. Mote, N. M. Filipov, Q. Zhao, S. Rayalam*, and H .J. Park*. (2020). Perinatal docosahexaenoic acid supplementation improves cognition and alters brain function organization in piglets. Nutrients, Epub: XXXXX; Accepted, July 10, 2020.
Grant Support
USDA (AFRI); NIFA (2020-67015-31301); “Dysregulated microbiome, metabolome, and microbiome-metabolome interactions in beef cattle grazing toxic tall fescue”; 7/01/20- 6/30/23; Role: PI.
USDA (AFRI); NIFA (2020-67017-30839); “Assessing the effects of maternal supplementation of eggs and docosahexaenoic acid on gut microbiome and cognitive development in an infant piglet model”; 4/01/20- 3/31/22; Role: Co-I.
NIH (NIEHS); 1R21ES026383-01; “Mycobacterium tuberculosis-manganese interactions and neurotoxicity”; 5/01/16 – 4/30/21; Role: PI.
Department of Defense (CDMRP); GWI150195; “Evaluation of treatment efficacy with a potent novel immunomodulatory glycan conjugate in Gulf War Illness models”; 9/01/16 – 8/31/20; Role: PI.
