Education
B.S. Biology, College of William and Mary 2002
M.S. Biology, Virginia Commonwealth University, 2005
Ph.D. Biochemistry, Virginia Commonwealth University School of Medicine, 2008
Areas of Expertise
Research: environmental impacts on spermatogenesis, stem cell biology, in vitro models of spermatogenesis
Teaching: reproductive and developmental toxicology, physiology
Honors, Awards, and Achievements
Cell Press Cell Reports Paper of the Year, 2012
Board Member of the Executive Committee for Public Policy for the American Society for Stem Cell Research
Vice Chair of the Regenerative Medicine and Stem Cell Biology Special Interest Group (RMSCBSIG)
Affiliations
American Society for Cell Biology
Society of Toxicology
International Society for Stem Cell Research
American Society for Reproductive Medicine
Course Instruction
Dr. Easley specializes in education related to reproductive and developmental toxicology, cell biology and physiology, stem cell biology and developmental biology.
Research Interests
Reproductive Toxicology, Male Infertility, Stem Cell Based Therapies, Regenerative Medicine, Drug Discovery (Male Contraceptives)
Selected Publications
Greeson KW, Fowler KL, Estave PM, Thompson SK, Wagner CR, Edenfield RC, Symosko KM, Steves AN, Marder EM, Terrell ML, Barton H, Marcus M, Koval M, Easley CA. † Detrimental Effects of Flame Retardant, PBB153, Exposure on Sperm and Future Generations. Under Review. Scientific Reports. 2020 May 22;10(1):8567. doi: 10.1038/s41598-020-65593-x. PMID: 32444626
Steves AN, Bradner JM, Fowler KL, Clarkson-Townsend D, Gill B, Turry A, Caudle WM, Miller GW, Chan AW, Easley CA. †. Ubiquitous Environmental Toxicants Impair Spermatogenesis in a Human Stem Cell Model. iScience. 2018 May 25;3:161-176. doi: 10.1016/j.isci.2018.04.014. PMID: 29901031
Easley IV CA†, Bradner JM, Moser A, Rickman CA, McEachin ZT, Merritt M, Hansen JM and Caudle WM. Assessing Reproductive Toxicity of Environmental Toxicants with a Novel in vitro Human Spermatogenic Model. Stem Cell Res. 2015 Mar 25;14(3):347-355. doi: 10.1016/j.scr.2015.03.002. PMID: 25863443.
Easley IV CA, Phillips BT, McGuire, MM, Barringer JM, Valli H, Hermann BP, Simerly CR, Miki T, Orwig KE, and Schatten GP. Direct Differentiation of Human Pluripotent Stem Cells into Haploid Spermatogenic Cells. Cell Reports 2012 Sep 27;2(3):440-6. doi: 10.1016/j.celrep.2012.07.015. Epub 2012 Aug 23. PMID: 22921399.
Grant Support
NIH/OD R01 09/06/2019-06/30/2023 (MPI: Easley, CA (contact), Chan AWS, and Orwig KE) Derivation of Functional Spermatogonia Stem Cells from Rhesus Macaque iPSCs
Bill and Melinda Gates Foundation GCE Phase Ib 06/01/2019-11/30/2020 (PI: Easley, CA) Developing a novel in vitro screening model to assess male contraceptives
Georgia Research Alliance Small Business Phase I 06/01/2019-12/31/2020 (MPI: Easley, CA (contact) and Chan AWS) Compositions and Methods for Improving Embryo Development
